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Combining ENDUR-ACIN® with exercise offers additional lipid benefits, study shows

Highlights

  • ENDUR-ACIN® improves lipid profiles and disease course in patients with coronary heart disease.
  • ENDUR-ACIN® combined with exercise therapy is more effective than ENDUR-ACIN® alone.
  • Recommending ENDUR-ACIN® as part of a diet and exercise program offers additional benefits for patients with moderate dyslipidemia.

Summary

This clinical trial compared the effects of exercise therapy, ENDUR-ACIN® treatment or the combination used for one year on the clinical course of coronary heart disease (CHD) in patients with moderate dyslipidemia.

For this study, researchers enrolled 93 patients with CHD. After one year, ENDUR-ACIN® treatment alone is reported to improve physical performance, arterial pressure and frequency of angina attacks.

However, the combination of ENDUR-ACIN® and exercise is reported to be more efficient than either monotherapy with improvements in physical performance, hemodynamics at rest and during exercise test, left ventricular systolic function, lipid profiles and clinical disease course.

These findings indicate that ENDUR-ACIN® combined with exercise therapy is more effective than ENDUR-ACIN® alone in improving the clinical course of coronary heart disease in patients with moderate dyslipidemia.

Reference

Oganov RG, Aronov DM, Krasnitskiĭ VB, et al. Exercise and nicotinic acid delayed action drug Enduracin: application in outpatient rehabilitation of patients with ischemic heart disease (in Russian; English abstract). Ter Arkh. 2004;76(4):54-9.

PMID: 15174324