Cholesterol and Lipid Metabolism STUDIES

Highlights A comparison of ENDUR-ACIN® therapy in younger vs. older (50-70 years) patients with dyslipidemia Effective treatment, ENDUR-ACIN® (1,500-2,000 mg/day) for 8 weeks Blood lipid profiles significantly improve, older patients...

Highlights Comparison of different ENDUR-ACIN® protocols (1,000-2,000 mg/day) over 20-week period 1,500 mg/day protocol is most effective and best tolerated with 96% adherence. Significant reductions in LDL cholesterol (-26%) and total-to-HDL cholesterol ratio...

Highlights Stepped-care, multi-drug therapy shows clinical benefits in patients with established CHD Therapeutic options include pravastatin, ENDUR-ACIN®, cholestyramine and gemfibrozil Combining ENDUR-ACIN® with pravastatin adds significant benefits for improving LDL...

Highlights ENDUR-ACIN® treatment (1,500-2,000 mg/day) significantly reduces total and LDL-cholesterol in people with high blood cholesterol (>225 mg/dl). Low dropout rate or 4.5% (4/89), primarily due to skin flushing or...

Highlights Effective niacin therapy (2 g/day) can be inexpensive ($7-10/month) “No-flush” inositol hexaniacinate products fail to contain free nicotinic acid, yet are comparatively expensive ($22/month) “No-flush” inositol hexaniacinate is an...