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Resveratrol improves endothelial function in patients with kidney disease and diabetes, study shows

Highlights Randomized, double-blind, placebo-controlled, cross-over trial involving 21 older adults with stage 3 CKD and diabetes Supplementation consist of ResVida 99% pure, all-trans resveratrol supplementation (200 mg/day, twice daily) for 6 weeks (treatment and matching...
on February 07, 2024

Compared to oral berberine, oral dihydroberberine achieves a higher blood berberine level with lower doses, study shows

Highlights Berberine supplementation has therapeutic value for glycemic control, but digestive upset and poor patient compliance is common. Compared to high-dose berberine (500 mg), low-dose dihydroberberine (100 or 200 mg) significantly (p<.05)...
on January 23, 2024

Pharmacokinetic profile of ENDUR-AMIDE® sustained-release niacinamide

Highlights Sustained-release ENDUR-AMIDE® and standard niacinamide pharmacokinetics studied in young men Low-dose preparations yield similar results High-dose preparations differ in several parameters (Cmax, AUC and Tmax) Summary The aim of...
on August 29, 2020

Niacin may reduce apoptosis, preclinical study shows

Highlights Nicotinic acid & niacinamide exert anti-apoptotic action Action appears to be multifactorial, including DNA repair Action appears unrelated to reducing oxidative stress Summary The aim of this in-vitro study...
on August 29, 2020

Vitamin C supplementation significantly reduces blood pressure in adults, meta-analysis shows

Highlights Meta-analysis of 29 randomized, controlled trials (1,407 adults) Vitamin C supplementation significantly reduces blood pressure Median dosage is 500 mg/day for 8 weeks Summary This meta-analysis was designed to...
on February 25, 2020