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 STUDIES

Pharmacokinetic profile of ENDUR-AMIDE® sustained-release niacinamide

Highlights Sustained-release ENDUR-AMIDE® and standard niacinamide pharmacokinetics studied in young men Low-dose preparations yield similar results High-dose preparations differ in several parameters (Cmax, AUC and Tmax) Summary The aim of...
on August 29, 2020

Niacin may reduce apoptosis, preclinical study shows

Highlights Nicotinic acid & niacinamide exert anti-apoptotic action Action appears to be multifactorial, including DNA repair Action appears unrelated to reducing oxidative stress Summary The aim of this in-vitro study...
on August 29, 2020

Vitamin C supplementation significantly reduces blood pressure in adults, meta-analysis shows

Highlights Meta-analysis of 29 randomized, controlled trials (1,407 adults) Vitamin C supplementation significantly reduces blood pressure Median dosage is 500 mg/day for 8 weeks Summary This meta-analysis was designed to...
on February 25, 2020

Vitamin C supplementation improves blood lipids in patients with dyslipidemia or diabetes, meta-analysis shows

Highlights Meta-analysis of 40 randomized, controlled trials with significant heterogeneity No overall significant effect of vitamin C supplementation on blood lipid levels Subgroup analyses shows significant effects in people with...
on February 25, 2020

Vitamin C improves endothelial function, especially in patients with cardiovascular disease, meta-analysis shows

Highlights Meta-analysis of 44 randomized, controlled trials Vitamin C improves endothelial function in a dose-dependent manner Patients at higher cardiovascular disease risk benefit more Summary This systematic review and meta-analysis...
on February 25, 2020
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